Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681996 | 0.91 | TLR8 (0.36) | TLR8HRH4 | |
| SCHEMBL7678787 | 0.82 | HPGD (0.34) | — | |
| SCHEMBL7676202 | 0.80 | PTGES (0.33) | HRH4 | |
| SCHEMBL7683018 | 0.78 | POLB (0.40) | — | |
| SCHEMBL7677420 | 0.77 | GLA (0.36) | TLR8 | |
| SCHEMBL27413423 | 0.76 | TLR8 (0.34) | TLR8 | |
| SCHEMBL7679216 | 0.75 | TP53 (0.33) | HRH4 | |
| SCHEMBL8784365 | 0.74 | HRH4 (0.34) | HRH4 | |
| SCHEMBL7676442 | 0.74 | NR1I3 (0.41) | — | |
| SCHEMBL7674269 | 0.74 | CGAS (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | disclosed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | disclosed |