Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.52 |
| ▸ | CDK4 | P11802 | 9/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676581 | 0.88 | CDK2 (0.54) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7677550 | 0.87 | CDK2 (0.58) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676327 | 0.85 | CDK2 (0.58) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676881 | 0.84 | CDK2 (0.41) | CDK2CDK4 | |
| SCHEMBL7678725 | 0.84 | CDK2 (0.54) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676795 | 0.84 | CDK2 (0.39) | CDK2CDK4 | |
| SCHEMBL7680801 | 0.81 | CDK2 (0.60) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7682151 | 0.80 | CDK2 (0.45) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7675176 | 0.80 | CDK2 (0.61) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7682025 | 0.80 | CDK2 (0.66) | CDK2CDK4CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |