Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676349 | 0.91 | CDK2 (0.42) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7682053 | 0.89 | CDK2 (0.40) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676377 | 0.89 | CDK2 (0.42) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7677654 | 0.86 | NTRK1 (0.33) | CDK2CDK4NTRK1CYP2C9DHFR | |
| SCHEMBL7680020 | 0.85 | CDK2 (0.41) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676916 | 0.85 | CDK2 (0.44) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676510 | 0.84 | CDK2 (0.47) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7682045 | 0.84 | CDK2 (0.43) | CDK2CDK4ALDH1A1PPARGCSNK1D | |
| SCHEMBL7676606 | 0.84 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676621 | 0.84 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |