Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683146 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7683152 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7689601 | 0.89 | HDAC11 (0.46) | MEN1KMT2ARARBTTRDPP4 | |
| SCHEMBL7689603 | 0.89 | HDAC11 (0.46) | MEN1KMT2ARARBTTRDPP4 | |
| SCHEMBL7689599 | 0.89 | HDAC11 (0.46) | MEN1KMT2ARARBTTRDPP4 | |
| SCHEMBL7683191 | 0.86 | RARB (0.53) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7683200 | 0.86 | RARB (0.53) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7683195 | 0.86 | RARB (0.53) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7683526 | 0.83 | HDAC11 (0.39) | MEN1KMT2ARARBTTRDPP4 | |
| SCHEMBL7683532 | 0.82 | RARA (0.39) | MEN1KMT2ARARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37947-E1 | Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2002-12-31 | — | — | US | disclosed |