Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 0.48 |
| ▸ | AKT2 | P31751 | 10/20 | 0.48 |
| ▸ | USP7 | Q93009 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466484 | 0.83 | AKT1 (0.60) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7467961 | 0.81 | AKT1 (0.56) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7676300 | 0.80 | AKT1 (0.44) | AKT1AKT2F2RL1 | |
| SCHEMBL7676578 | 0.79 | AKT1 (0.41) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7683359 | 0.79 | CDK2 (0.59) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7678849 | 0.76 | AKT1 (0.55) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7676382 | 0.76 | USP7 (0.59) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7473818 | 0.75 | SRD5A2 (0.43) | AKT1AKT2USP7CDK2CDK4 | |
| SCHEMBL7682754 | 0.75 | CDK2 (0.58) | AKT1AKT2CDK2CDK4 | |
| SCHEMBL7673469 | 0.75 | CDK2 (0.57) | AKT1AKT2USP7CDK2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |