Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 14/20 | 0.44 |
| ▸ | AKT2 | P31751 | 14/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693622 | 0.85 | AKT1 (0.48) | AKT1AKT2F2RL1RXFP1 | |
| SCHEMBL7683226 | 0.80 | AKT1 (0.48) | AKT1AKT2F2RL1 | |
| SCHEMBL7676578 | 0.73 | AKT1 (0.41) | AKT1AKT2F2RL1RXFP1KDM4E | |
| SCHEMBL15123598 | 0.68 | AKT1 (0.58) | AKT1AKT2 | |
| SCHEMBL19135994 | 0.66 | ALDH1A1 (0.49) | AKT1AKT2KDM4EALDH1A1GAA | |
| SCHEMBL4449884 | 0.65 | MAPT (0.56) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL15050025 | 0.64 | AKT1 (0.58) | AKT1AKT2F2RL1KDM4EALDH1A1 | |
| SCHEMBL15071104 | 0.64 | HPGD (0.52) | AKT1AKT2F2RL1ALDH1A1GAA | |
| SCHEMBL7466484 | 0.63 | AKT1 (0.60) | AKT1AKT2KDM4EALDH1A1TP53 | |
| SCHEMBL25391 | 0.63 | F2RL1 (0.58) | AKT1AKT2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |