SCHEMBL7683364

SCHEMBL7683364

COC(OC)C1CCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.46
PDPK1 O15530 1/20 0.46
SIGMAR1 Q99720 4/20 0.41
PIN1 Q13526 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
HIF1A Q16665 1/20 0.40
PRCP P42785 1/20 0.40
CYP11B2 P19099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735161 0.89 IDO1 (0.49) IDO1PDPK1
SCHEMBL30298334 0.79 PRCP (0.52) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL30298337 0.79 PRCP (0.52) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL835606 0.79 PRCP (0.52) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL15503486 0.77 SLC7A5 (0.39) SIGMAR1
SCHEMBL11498923 0.76 HTR2A (0.52) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL19852531 0.76 PDPK1 (0.47) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL21465991 0.76 PDPK1 (0.47) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL13115630 0.76 HTR2A (0.52) IDO1PDPK1SIGMAR1PRCPCYP11B2
SCHEMBL5748401 0.76 PDPK1 (0.47) IDO1PDPK1SIGMAR1PRCPCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362141-B1 ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2002-03-26 US disclosed
US-6342612-B1 FRAGRANCES INTERNATIONAL FLAVORS & FRAGRANCES INC. 2002-01-29 US disclosed
EP-0546573-B1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC (US) 1998-03-11 EP disclosed
CN-1035385-C Process for preparing stabilized polyolefins HIMONT INC (US) 1997-07-09 CN disclosed
EP-0361494-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1996-02-07 EP disclosed
EP-0434082-B1 Components and catalysts for the polymerization of olefins HIMONT INC (US) 1995-10-25 EP disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
CN-1022326-C Components and catalysts for polymerization of olefins HIMONT INC (US) 1993-10-06 CN disclosed
CN-1074222-A Process for preparing stabilized polyolefins and products thereof HIMONT INC (US) 1993-07-14 CN disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
US-4971937-A COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS HIMONT INCORPORATED (US) 1990-11-20 US disclosed
EP-0361494-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-04 EP disclosed