SCHEMBL8735161

SCHEMBL8735161

COC(OC)C1CCCc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.49
GID4 Q8IVV7 1/20 0.46
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CHRNA7 P36544 1/20 0.40
PDPK1 O15530 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7683364 0.89 IDO1 (0.46) IDO1PDPK1
SCHEMBL3000155 0.80 IDO1 (0.49) IDO1GID4CHRNA7PDPK1
SCHEMBL3296406 0.80 IDO1 (0.49) IDO1GID4CHRNA7PDPK1
SCHEMBL15503516 0.78 FFAR1 (0.39) IDO1GID4MEN1KMT2A
SCHEMBL2094512 0.78 IDO1 (0.44) IDO1GID4TSHR
SCHEMBL15540606 0.77 IDO1 (0.50) IDO1GID4CHRNA7PDPK1
SCHEMBL4081534 0.77 IDO1 (0.46) IDO1GID4TSHRCHRNA7PDPK1
SCHEMBL13006752 0.77 IDO1 (0.50) IDO1GID4CHRNA7PDPK1
Hydrogen Peroxide SCHEMBL9456544 0.77 IDO1 (0.46) IDO1TSHRMEN1KMT2A
SCHEMBL21400761 0.77 IDO1 (0.49) IDO1MEN1KMT2ACHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546573-B1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC (US) 1998-03-11 EP disclosed
EP-0434082-B1 Components and catalysts for the polymerization of olefins HIMONT INC (US) 1995-10-25 EP disclosed
EP-0362705-B1 Catalysts for the polymerization of olefins HIMONT INC (US) 1995-01-11 EP disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed