SCHEMBL7683514

SCHEMBL7683514

N=C(N)NCC1CCC(C(=O)O)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
PLG P00747 1/20 0.44
PLAT P00750 1/20 0.44
LMNA P02545 1/20 0.44
ANPEP P15144 2/20 0.37
ENPEP Q07075 1/20 0.37
KMT2A Q03164 3/20 0.36
CYP2D6 P10635 1/20 0.34
EPHX1 P07099 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GABRR1 P24046 1/20 0.33
ALB P02768 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C9 P11712 1/20 0.33
ACE P12821 1/20 0.33
CYP2C19 P33261 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C1 Q04828 1/20 0.32
VCP P55072 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26073040 1.00 TDP1 (0.46) TDP1PLGPLATLMNAANPEP
SCHEMBL483347 0.89 TDP1 (0.53) TDP1PLGPLATLMNAANPEP
SCHEMBL483345 0.89 TDP1 (0.53) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL26072375 0.89 ANPEP (0.47) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL30596205 0.89 ANPEP (0.47) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL7443981 0.88 TDP1 (0.52) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL11285151 0.88 TDP1 (0.52) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL5505595 0.88 TDP1 (0.52) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL11285176 0.88 TDP1 (0.52) TDP1PLGPLATLMNAANPEP
Hydrochloric Acid SCHEMBL10894938 0.86 TDP1 (0.50) TDP1PLGPLATLMNAANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119486730-A Tranexamic acid arginine and histidine mimics as therapeutic agents 传明科技有限责任公司 2025-02-18 CN claimed
EP-4499234-A1 TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS Tranexamic Technologies, LLC (US) 2025-02-05 EP claimed
WO-2023192165-A1 TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS TRANEXAMIC TECHNOLOGIES, LLC (US) 2023-10-05 WO claimed
CN-119486730-A Tranexamic acid arginine and histidine mimics as therapeutic agents 传明科技有限责任公司 2025-02-18 CN disclosed
CN-119486730-A Tranexamic acid arginine and histidine mimics as therapeutic agents 传明科技有限责任公司 2025-02-18 CN disclosed
US-6410594-B1 VIRICIDES BIOCRYST PHARMACEUTICALS, INC. 2002-06-25 US disclosed