SCHEMBL483347

SCHEMBL483347

N=C(N)NCC1CCC(C(=O)O)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
PLG P00747 1/20 0.52
PLAT P00750 1/20 0.52
LMNA P02545 1/20 0.52
KMT2A Q03164 3/20 0.43
ANPEP P15144 1/20 0.42
ENPEP Q07075 1/20 0.42
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2D6 P10635 1/20 0.40
EPHX1 P07099 1/20 0.39
VCP P55072 4/20 0.38
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483345 1.00 TDP1 (0.53) TDP1PLGPLATLMNAKMT2A
Hydrochloric Acid SCHEMBL11285151 0.98 TDP1 (0.52) TDP1PLGPLATLMNAKMT2A
Hydrochloric Acid SCHEMBL5505595 0.98 TDP1 (0.52) TDP1PLGPLATLMNAKMT2A
Hydrochloric Acid SCHEMBL11285176 0.98 TDP1 (0.52) TDP1PLGPLATLMNAKMT2A
Hydrochloric Acid SCHEMBL7443981 0.98 TDP1 (0.52) TDP1PLGPLATLMNAKMT2A
Hydrochloric Acid SCHEMBL10894938 0.96 TDP1 (0.50) TDP1PLGPLATLMNAKMT2A
SCHEMBL11280746 0.92 TDP1 (0.46) TDP1PLGPLATLMNAKMT2A
SCHEMBL7683514 0.89 TDP1 (0.46) TDP1PLGPLATLMNAKMT2A
SCHEMBL26073040 0.89 TDP1 (0.46) TDP1PLGPLATLMNAKMT2A
SCHEMBL8596242 0.85 TDP1 (0.76) TDP1PLGPLATLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228807-A1 TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS TRANEXAMIC TECHNOLOGIES, LLC (US) 2025-07-17 US claimed
CN-119486730-A Tranexamic acid arginine and histidine mimics as therapeutic agents 传明科技有限责任公司 2025-02-18 CN claimed
EP-4499234-A1 TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS Tranexamic Technologies, LLC (US) 2025-02-05 EP claimed
WO-2023192165-A1 TRANEXAMIC CLASS ARGININE AND HISTIDINE MIMICS AS THERAPEUTIC AGENTS TRANEXAMIC TECHNOLOGIES, LLC (US) 2023-10-05 WO claimed
EP-0870500-B1 ANTI-HELICOBACTER PYLORI AGENT NAGASE CHEMTEX CORP (JP) 2008-02-20 EP claimed
US-20060105959-A1 Organic compounds with biological action as thrombin inhibitors and use thereof CPI CREATIVE PHARMA INTERNATIONAL GMBH (DE) 2006-05-18 US claimed
EP-0452145-B1 Coated composition and its preparation process SHIONOGI & CO (JP) 1996-11-13 EP claimed
EP-0193965-B1 NOVEL GUANIDINOMETHYLCYCLOHEXANCARBOXYLIC ACID COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM KANEBO, LTD. (JP) 1988-11-30 EP claimed
EP-0078599-B1 COMPLEX COMPOUNDS BASED ON CYCLODEXTRINS TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) 1986-11-12 EP claimed
EP-0193965-A2 Novel guanidinomethylcyclohexancarboxylic acid compounds, processes for preparing them, and pharmaceutical compositions containing them KANEBO, LTD. (JP) 1986-09-10 EP claimed
US-4220662-A TREATING BACTERIAL INFECTIONS COOK ELTON S 1980-09-02 US claimed
JP-62039561-A None JP disclosed
JP-56092260-A None JP disclosed
JP-57197256-A None JP disclosed
JP-57016856-A None JP disclosed
JP-S5716856-A 4-GUANIDINOMETHYLCYCLOHEXANECARBOXYLIC ACID ESTER AND ITS PREPARATION TEIKOKU CHEM IND CORP LTD 1982-01-28 JP disclosed
JP-S5716855-A 4-GUANIDINOMETHYLCYCLOHEXANECARBOXYLIC ACID ESTER AND ITS PREPARATION TEIKOKU CHEM IND CORP LTD 1982-01-28 JP disclosed
JP-S5692260-A CYCLOHEXANECARBOXYLIC ESTER AND ITS PREPARATION NIPPON CHEMIPHAR CO LTD 1981-07-25 JP disclosed
US-4220662-A TREATING BACTERIAL INFECTIONS COOK ELTON S 1980-09-02 US disclosed
JP-1056614-A 0001-01-01 JP disclosed