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Sugi Predict / Compounds / SCHEMBL7684142

SCHEMBL7684142

SCHEMBL7684142

C/C(=C(\F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(N)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 1.00
▸ F2 P00734 3/20 0.85
▸ PRSS1 P07477 3/20 0.85
▸ KCNH2 Q12809 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7684143 1.00 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7688293 0.92 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7690621 0.92 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7690626 0.84 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7679952 0.80 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7684856 0.79 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7684861 0.79 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7690406 0.79 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL7690410 0.79 F10 (1.00) F10F2PRSS1KCNH2
SCHEMBL4348658 0.76 F10 (0.85) F10F2PRSS1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399627-B1 ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES COR THERAPEUTICS, INC. 2002-06-04 — — US disclosed
EP-1159264-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS, INC. (US) 2001-12-05 — — EP disclosed
WO-2000047554-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS INC. (US) 2000-08-17 — — WO disclosed