SCHEMBL7684675

SCHEMBL7684675

C/C(=C/C(C)(C)c1ccccc1)C(=O)OOC(C)(C)OC(=O)OC(C)(C)OOC(=O)/C(C)=C\C(C)(C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KMT2A Q03164 2/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.33
KCNN4 O15554 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763275 0.85 CYP2D6 (0.36) HIF1AMAPK1CYP2D6
SCHEMBL7692607 0.80 CYP1A2 (0.32) CYP2C19HIF1AALDH1A1TSHRKMT2A
SCHEMBL8762557 0.78
SCHEMBL8524781 0.77 KMT2A (0.33) CYP2C19HIF1AALDH1A1TSHRHSD17B10
SCHEMBL10596750 0.76 TSHR (0.36) ALDH1A1TSHRTDP1KMT2AMAPT
SCHEMBL9799297 0.74 AKR1C3 (0.48) CYP2C19HIF1AALDH1A1KMT2AMAPT
SCHEMBL1469914 0.74 AKR1C3 (0.48) CYP2C19HIF1AALDH1A1KMT2AMAPT
SCHEMBL7691672 0.74 GRIN2D (0.30) CYP1A2CYP2D6
SCHEMBL7692276 0.74 KMT2A (0.42) CYP2C19HIF1AALDH1A1TSHRHSD17B10
SCHEMBL7691599 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0608856-B1 Graft precursor and process for producing grafted aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-09 EP disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0435340-B1 Thermoplastic resin compositions NIPPON PETROCHEMICALS CO LTD (JP) 1996-05-01 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438098-A Blend of polyarylene sulfie;, polycarbonater and/or acrylonitrile-butadiene-styrene resin, and epoxy group containing defin graft polymer as compatibilizer NIPPON PETROCHEMICALS CO., LTD. (JP) 1995-08-01 US disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0423767-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-04-24 EP disclosed
EP-0412572-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-13 EP disclosed
US-4987165-A MULTIPHASE COMPATIBILIZER FOR BLEND OF POLYSULFONE AND ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-01-22 US disclosed
US-4983663-A Polymer alloy of an ABS terpolymer, an aromatic polyester or polyamide and an epoxy-containing graft addition polymer also containing an unsaturated peroxide; impact strength; molding materials NIPPON PETROCHEMICALS CO. (JP) 1991-01-08 US disclosed
US-4962148-A HIGH STRENGTH, CHEMICAL RESISTANCE, MOLDING MATERIALS NIPPON PETROCHEMICALS CO., LTD (JP) 1990-10-09 US disclosed
US-4923956-A Containing free radical polymerizable organic peroxide NIPPON OIL AND FATS CO., LTD. (JP) 1990-05-08 US disclosed
EP-0361400-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-04-04 EP disclosed
EP-0314188-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed