SCHEMBL7692276

SCHEMBL7692276

C=C(C(=O)OOC(C)(C)OC(=O)OC(C)(C)OOC(=O)C(=C)C(C)(C)c1ccccc1)C(C)(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.35
KCNN4 O15554 1/20 0.34
HDAC3 O15379 2/20 0.33
HDAC4 P56524 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC7 Q8WUI4 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC10 Q969S8 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC9 Q9UKV0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853450 0.85 CYP2D6 (0.38) MAPTHIF1AALDH1A1MAPK1CYP2D6
SCHEMBL2772373 0.78 MAPT (0.39) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL9242882 0.77 MAPT (0.43) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL10701124 0.76 MAPT (0.37) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL9862027 0.74 ALDH1A1 (0.41) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL10787300 0.74 MAPT (0.47) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL10455049 0.74 KMT2A (0.36) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL7684675 0.74 CYP2C19 (0.36) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL28722852 0.73 MAPT (0.53) KMT2AMAPTCYP2C19HIF1AALDH1A1
SCHEMBL5071313 0.73 KMT2A (0.57) KMT2AMAPTCYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0608856-B1 Graft precursor and process for producing grafted aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-09 EP disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0435340-B1 Thermoplastic resin compositions NIPPON PETROCHEMICALS CO LTD (JP) 1996-05-01 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438098-A Blend of polyarylene sulfie;, polycarbonater and/or acrylonitrile-butadiene-styrene resin, and epoxy group containing defin graft polymer as compatibilizer NIPPON PETROCHEMICALS CO., LTD. (JP) 1995-08-01 US disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0334296-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-09-27 EP disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0307802-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-22 EP disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304040-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0295706-A2 Thermoplastic resin composition and method for preparing the same Nippon Petrochemicals Co., Ltd. (JP) 1988-12-21 EP disclosed
EP-0289933-A2 Graft polymerization precurser and method manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0277608-A2 Graft polymerization preformer and method of manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-10 EP disclosed