Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326003 | 0.83 | GAA (0.94) | GAAMAPTHTTLMNANPSR1 | |
| SCHEMBL10357803 | 0.77 | GBA1 (0.77) | GAAMAPTHTTLMNANPSR1 | |
| SCHEMBL10745289 | 0.76 | KMT2A (0.52) | GAAMAPTHTTLMNANPSR1 | |
| SCHEMBL7565070 | 0.76 | MAPT (0.64) | GAAMAPTLMNANPSR1KMT2A | |
| SCHEMBL25773032 | 0.74 | MAPT (0.59) | GAAMAPTHTTLMNANPSR1 | |
| SCHEMBL17988269 | 0.74 | NPSR1 (1.00) | GAAMAPTHTTLMNANPSR1 | |
| SCHEMBL13621755 | 0.74 | PTPN11 (0.53) | GAAMAPTHTTLMNAKMT2A | |
| SCHEMBL10785192 | 0.73 | NPC1 (0.57) | GAAMAPTLMNANPSR1KMT2A | |
| SCHEMBL16750604 | 0.73 | TTK (0.53) | GAAMAPTHTTLMNANPSR1 | |
| SCHEMBL25284382 | 0.73 | HPGD (0.51) | GAAMAPTHTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | claimed |