Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 11/20 | 0.42 |
| ▸ | RARG | P13631 | 10/20 | 0.42 |
| ▸ | RARB | P10826 | 9/20 | 0.42 |
| ▸ | IKBKB | O14920 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 6/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683402 | 0.90 | RARG (0.46) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7683390 | 0.90 | RARG (0.46) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7685636 | 0.87 | RARA (0.55) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7685633 | 0.87 | RARA (0.55) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7685634 | 0.87 | RARA (0.55) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7690025 | 0.86 | RARA (0.44) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7690029 | 0.86 | RARA (0.44) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7690023 | 0.86 | RARA (0.44) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7684901 | 0.86 | RARA (0.43) | RARARARGRARBIKBKBRXRA | |
| SCHEMBL7686279 | 0.82 | RARA (0.48) | RARARARGRARBIKBKBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37947-E1 | Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2002-12-31 | — | — | US | disclosed |