Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686582 | 0.89 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL6986689 | 0.88 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7684537 | 0.88 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL6984017 | 0.86 | CRHR1 (0.75) | CRHR1 | |
| SCHEMBL7687005 | 0.85 | CRHR1 (0.77) | CRHR1 | |
| SCHEMBL7683418 | 0.84 | CRHR1 (0.73) | CRHR1 | |
| SCHEMBL7680488 | 0.84 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL9046910 | 0.84 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL7678011 | 0.82 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7696945 | 0.82 | CRHR1 (0.69) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | claimed |
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | disclosed |