Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23874539 | 0.78 | IDO1 (0.39) | IDO1DRD3 | |
| SCHEMBL8562992 | 0.78 | EPHX2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11467676 | 0.73 | IDO1 (0.41) | IDO1DRD3PLAU | |
| SCHEMBL30298338 | 0.73 | IDO1 (0.41) | IDO1DRD3PLAU | |
| SCHEMBL19655060 | 0.72 | PLAU (0.44) | PLAU | |
| SCHEMBL12804575 | 0.70 | HTR2A (0.50) | IDO1PLAU | |
| SCHEMBL12936160 | 0.70 | HTR2A (0.50) | IDO1PLAU | |
| SCHEMBL5724797 | 0.70 | GRM7 (0.41) | IDO1DRD3 | |
| SCHEMBL5724898 | 0.70 | IDO1 (0.38) | IDO1DRD3PLAUPNMT | |
| SCHEMBL9367720 | 0.69 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649101-A | Catalyst and process for preparing same | BOREALIS AG | 2014-03-19 | — | — | CN | disclosed |
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |