Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27392883 | 0.84 | CYP1A2 (0.50) | ALDH1A1HSD11B1MEN1KMT2APOLB | |
| SCHEMBL4630040 | 0.84 | CYP1A2 (0.50) | ALDH1A1HSD11B1MEN1KMT2APOLB | |
| SCHEMBL8364745 | 0.82 | TSHR (0.52) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL4630784 | 0.81 | HDAC1 (0.57) | ALDH1A1MEN1KMT2AHSD17B10HDAC3 | |
| SCHEMBL7744597 | 0.79 | POLB (0.44) | ALDH1A1HSD11B1MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8365023 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL7744594 | 0.77 | CYP1A2 (0.43) | ALDH1A1HSD11B1MEN1KMT2APOLB | |
| SCHEMBL8368905 | 0.74 | KMT2A (0.43) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL5170026 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL13774961 | 0.73 | ALDH1A1 (0.71) | ALDH1A1POLBGAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465489-B1 | SUCH AS 1-BENZOYL-3-(3,4-DICHLOROPHENYL)-3-(3-(4-(N',N'-DIMETHYLUREIDO)-4 -PHENYLPIPERIDIN-1-)PROPYL)PIPERIDINE; PSYCHIATRIC AND PSYCHOSOMATIC ILLNESSES, HYPERTENSION, CENTRAL OR PERIPHERAL PATHOLOGY | SANOFI-SYNTHELABO (FR) | 2002-10-15 | — | — | US | disclosed |