Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676234 | 0.92 | MAPK1 (0.32) | CTSKMAPK1NPSR1 | |
| SCHEMBL4070227 | 0.82 | CCR1 (0.31) | CCR1 | |
| SCHEMBL4068119 | 0.79 | CCR1 (0.39) | CCR1SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL4063221 | 0.73 | CCR1 (0.32) | CCR1 | |
| SCHEMBL4061786 | 0.71 | PTPRA (0.37) | CCR1 | |
| SCHEMBL5795615 | 0.66 | DPP4 (0.40) | CTSKMAPK1NPSR1 | |
| SCHEMBL6832227 | 0.65 | IL1RN (0.39) | CCR1 | |
| SCHEMBL7281506 | 0.64 | CA2 (0.42) | SLC1A3SLC1A2SLC1A1CTSKMAPK1 | |
| SCHEMBL9079440 | 0.64 | DPP4 (0.38) | MAPK1NPSR1 | |
| SCHEMBL9079444 | 0.64 | DPP4 (0.38) | MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403587-B1 | AUTOIMMUNE DISEASES, ACUTE AND CHRONIC INFLAMMATORY CONDITIONS, ALLERGIC CONDITIONS, INFECTION ASSOCIATED WITH INFLAMMATION, VIRAL, TRANSPLANTATION TISSUE REJECTION, ATHEROSCLEROSIS, RESTENOSIS, HIV INFECTIVITY, AND | PFIZER INC. | 2002-06-11 | — | — | US | disclosed |