Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 11/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.70 |
| ▸ | PTGIR | P43119 | 9/20 | 0.69 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4689116 | 0.99 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4689671 | 0.96 | ADRA2A (0.68) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL7686408 | 0.94 | ADRA2A (0.65) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| Hydrochloric Acid SCHEMBL4689825 | 0.93 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4686075 | 0.92 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4692818 | 0.88 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4691558 | 0.85 | PTGIR (0.76) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL7677405 | 0.84 | PTGIR (0.58) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL7685721 | 0.84 | ADRA2A (0.61) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL13017291 | 0.84 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CPTGIRGPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472536-B1 | SUCH AS 2-(4-(4-CYCLOPENTYLOXYBENZYL)PHENYL)AMINO-IMIDAZOLINE; ANTINOCICEPTIVE AGENTS; IP RECEPTOR ANTAGONISTS; TREATING INFLAMMATORY PAIN | SYNTEX (U.S.A.) LLC | 2002-10-29 | — | — | US | claimed |