Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PLTP | P55058 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403637 | 0.95 | TRPV4 (0.36) | TRPV4GAAMAPTTP53PLTP | |
| SCHEMBL1008694 | 0.95 | TRPV4 (0.36) | TRPV4GAAMAPTTP53PLTP | |
| SCHEMBL7682713 | 0.94 | TRPV4 (0.35) | TRPV4GAAMAPTTP53SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL226079 | 0.92 | TRPV4 (0.34) | TRPV4MAPTTP53SMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30480661 | 0.92 | TRPV4 (0.34) | TRPV4MAPTTP53SMN1; SMN2ALDH1A1 | |
| Diethylamine SCHEMBL7031731 | 0.92 | TRPV4 (0.34) | TRPV4GAAMAPTTP53ALDH1A1 | |
| SCHEMBL7688727 | 0.91 | TRPV4 (0.36) | TRPV4MAPTTP53PLTPLMNA | |
| Monoethanolamine SCHEMBL7032257 | 0.91 | TRPV4 (0.34) | TRPV4MAPTTP53PLTPLMNA | |
| SCHEMBL7686443 | 0.91 | TRPV4 (0.36) | TRPV4GAAMAPTTP53PLTP | |
| Monoethanolamine SCHEMBL7031750 | 0.90 | TRPV4 (0.33) | TRPV4PLTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | claimed |
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |