Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929357 | 0.98 | RAD52 (0.57) | RAD52ACHEMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5929369 | 0.97 | RAD52 (0.56) | RAD52ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL5929400 | 0.90 | RAD52 (0.54) | RAD52MEN1KMT2AALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL5929401 | 0.89 | RAD52 (0.53) | RAD52MEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL16583873 | 0.82 | SIGMAR1 (0.45) | RAD52MEN1KMT2AHRH3DRD3 | |
| SCHEMBL14304586 | 0.81 | MEN1 (0.47) | ACHEMEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL5929374 | 0.80 | SRC (0.47) | RAD52KMT2AALDH1A1HRH3GAA | |
| SCHEMBL791880 | 0.78 | DRD3 (0.61) | ACHEMEN1KMT2AHRH3MAPT | |
| SCHEMBL4922627 | 0.76 | DRD3 (0.63) | ACHEMEN1KMT2AHRH3MAPT | |
| SCHEMBL6369704 | 0.76 | NQO2 (0.47) | RAD52ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568686-A1 | n-alkylaminated secondary paraphenylendiamine, which is ortho- and/or meta-substituted, dying composition comprising this paraphenylendiamine, methods based on this composition and uses | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-8129396-B2 | 2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors | TELIK, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20100081653-A1 | 2-[1H-Benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors | TELIK, INC. | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081653-A1 | 2-[1H-Benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors | MAP3K2, MAP4K2, MAP3K12 | RAD52 1500/4885ACHE 4105/4885MEN1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.