Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256527 | 0.94 | HTR1D (0.43) | HTR1DKMOCNR1EEF2KDYRK3 | |
| SCHEMBL7256498 | 0.80 | EEF2K (0.46) | HTR1DKMOEEF2KDYRK3JAK2 | |
| SCHEMBL7258088 | 0.80 | HTR1D (0.57) | HTR1DKMOMAP4K4HTR7BRD4 | |
| SCHEMBL7253556 | 0.78 | HTR1D (0.46) | HTR1DKMOEEF2KDYRK3JAK2 | |
| SCHEMBL7253008 | 0.77 | HTR1D (0.62) | HTR1DKMOEEF2KDYRK3JAK2 | |
| SCHEMBL7253520 | 0.77 | HTR1D (0.44) | HTR1DKMOEEF2KDYRK3JAK2 | |
| SCHEMBL7253656 | 0.76 | HTR7 (0.57) | HTR1DHTR7GRIN2B | |
| SCHEMBL7253427 | 0.76 | HTR7 (0.55) | HTR1DHTR7 | |
| SCHEMBL7253398 | 0.75 | HTR1D (0.48) | HTR1DKMOEEF2KDYRK3JAK2 | |
| SCHEMBL7252935 | 0.75 | HTR7 (0.54) | HTR1DHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380242-B1 | FOR DIAGNOSIS AND THERAPY OF CENTRAL NERVOUS SYSTEM CONDITIONS | NPS ALLELIX CORP. (CA) | 2002-04-30 | — | — | US | disclosed |