Oleic Acid

Oleic Acid

SCHEMBL7686924

CCCCCCCCC=CCCCCCCCC(=O)[O-].O=S(=O)(O)O.[Na+]

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.58
SLC6A2 known ✓ P23975 1/20 0.58
FABP3 P05413 9/20 0.83
TERT O14746 3/20 0.58
MAPT P10636 2/20 0.58
BLM P54132 2/20 0.58
HSD17B10 Q99714 2/20 0.58
FABP4 P15090 2/20 0.58
GMNN O75496 1/20 0.58
USP2 O75604 1/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
POLB P06746 1/20 0.58
CYP2C9 P11712 1/20 0.58
ALOX15 P16050 1/20 0.58
APEX1 P27695 1/20 0.58
CYP2C19 P33261 1/20 0.58
RECQL P46063 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
DUSP3 P51452 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleic Acid SCHEMBL11491299 1.00 FABP3 (0.83) FABP3TERTMAPTBLMHSD17B10
Oleic Acid SCHEMBL28111400 0.97 FABP3 (0.86) FABP3TERTMAPTBLMHSD17B10
Oleic Acid SCHEMBL28571631 0.95 FABP3 (0.80) FABP3TERTMAPTBLMHSD17B10
Oleic Acid SCHEMBL7686918 0.93 FABP3 (0.83) FABP3TERTMAPTBLMHSD17B10
Nervonic Acid SCHEMBL25231555 0.93 FABP3 (0.96) FABP3TERTMAPTBLMHSD17B10
Palmitoleic Acid SCHEMBL25179789 0.93 FABP3 (0.96) FABP3TERTMAPTBLMHSD17B10
Oleic Acid SCHEMBL873182 0.93 FABP3 (0.96) FABP3TERTMAPTBLMHSD17B10
SCHEMBL25400903 0.93 FABP3 (0.96) FABP3TERTMAPTBLMHSD17B10
Palmitoleic Acid SCHEMBL141874 0.93 FABP3 (0.96) FABP3TERTMAPTBLMHSD17B10
Oleic Acid SCHEMBL9516126 0.93 FABP3 (0.96) FABP3TERTMAPTBLMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110508402-B Low-temperature-resistant double-acid-salt rare earth ore flotation collector and preparation method and application thereof 中国地质科学院矿产综合利用研究所 2021-08-24 CN claimed
CN-110508402-B Low-temperature-resistant double-acid-salt rare earth ore flotation collector and preparation method and application thereof 中国地质科学院矿产综合利用研究所 2021-08-24 CN disclosed
CN-110508402-B Low-temperature-resistant double-acid-salt rare earth ore flotation collector and preparation method and application thereof 中国地质科学院矿产综合利用研究所 2021-08-24 CN disclosed
CN-111363382-A Preparation method and application of calcium carbonate/calcium silicate/silicon oxide material 山东宝龙达实业集团有限公司 2020-07-03 CN disclosed
CN-110508402-A Low-temperature-resistant double-acid-salt rare earth ore flotation collector and preparation method and application thereof INST OF MULTIPURPOSE UTILIZATION OF MINERAL RESOURCES CHINESE ACADEMY OF GEOLOGICAL SCIENCES 2019-11-29 CN disclosed
US-9328228-B2 Chloroprene rubber composition and adhesive composition using said chloroprene rubber composition DENKA COMPANY LIMITED (JP) 2016-05-03 US disclosed
US-20160017130-A1 CHLOROPRENE RUBBER COMPOSITION AND ADHESIVE COMPOSITION USING SAID CHLOROPRENE RUBBER COMPOSITION DENKA COMPANY LIMITED (JP) 2016-01-21 US disclosed
CN-104479411-A Surface modification method of special nano calcium carbonate for silicone sealants GUANGXI HUANA NEW MATERIAL TECHNOLOGY CO LTD 2015-04-01 CN disclosed
US-6335391-B1 LATEX FOR ADHESIVE WHICH COMPRISES COPOLYMER CONSISTING OF 2,3-DICHLORO-1,3-BUTADIENE UNITS, 1,2-DICHLORO-1,3-BUTADIENE UNITS AND 1,3-DICHLORO-1,3-BUTADIENE UNITS TOSOH CORPORATION (JP) 2002-01-01 US disclosed
US-4211759-A High-density sodium perborate and method of preparation PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1980-07-08 US disclosed