Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 15/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683372 | 0.85 | CASP1 (0.54) | CASP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7676856 | 0.83 | CASP1 (0.46) | CASP1CASP3 | |
| SCHEMBL7435530 | 0.82 | CYP1A2 (0.63) | CASP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7686427 | 0.82 | CASP1 (0.48) | CASP1CASP3PPARA | |
| SCHEMBL7429152 | 0.81 | CYP1A2 (0.60) | CASP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7431720 | 0.80 | CASP1 (0.55) | CASP1CASP3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7443101 | 0.80 | CASP1 (0.53) | CASP1CASP3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7686976 | 0.80 | CASP1 (0.51) | CASP1CASP3PPARA | |
| SCHEMBL7432412 | 0.80 | CYP1A2 (0.57) | CASP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7687234 | 0.80 | CASP1 (0.52) | CASP1CASP3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |