Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionamide SCHEMBL28815857 | 0.85 | TSHR (0.48) | TSHRNOTUMRIPK1MTNR1AMTNR1B | |
| Acetic Acid SCHEMBL817975 | 0.84 | TSHR (0.57) | TSHRNOTUMRIPK1MTNR1AMTNR1B | |
| Acetamide SCHEMBL5312159 | 0.82 | TSHR (0.55) | TSHRNOTUMRIPK1MTNR1AMTNR1B | |
| Alcohol SCHEMBL1872106 | 0.81 | TSHR (0.60) | TSHRNOTUMRIPK1MTNR1AMTNR1B | |
| Acetic Acid SCHEMBL3435922 | 0.79 | TSHR (0.65) | TSHRNOTUMRIPK1MTNR1AMTNR1B | |
| Butane SCHEMBL2150151 | 0.79 | TSHR (0.63) | TSHRRIPK1ALDH1A1CYP2A6MAOA | |
| Methyl Alcohol SCHEMBL28873001 | 0.78 | TSHR (0.71) | TSHRNOTUMRIPK1CYP2A6MAOA | |
| Methacrylic Acid SCHEMBL8982198 | 0.77 | TSHR (0.48) | TSHRNOTUMRIPK1MTNR1AMTNR1B | |
| Urea SCHEMBL5312853 | 0.77 | TSHR (0.60) | TSHRNOTUMRIPK1ALDH1A1CYP2A6 | |
| Alcohol SCHEMBL10885293 | 0.77 | TSHR (0.68) | TSHRNOTUMRIPK1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |