SCHEMBL7687261

SCHEMBL7687261

COC=C(Oc1ccc(Cl)cc1COC(C)=O)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
POLB P06746 3/20 0.39
HPGD P15428 2/20 0.39
TP53 P04637 1/20 0.39
ADRB2 P07550 1/20 0.38
GAA P10253 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 2/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 5/20 0.36
LMNA P02545 2/20 0.34
AMY1A P0DUB6 1/20 0.34
MAPK1 P28482 1/20 0.34
THRB P10828 1/20 0.34
S1PR4 O95977 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7687260 1.00 SMN1; SMN2 (0.42) SMN1; SMN2POLBHPGDTP53ADRB2
SCHEMBL7687263 0.90 SMN1; SMN2 (0.43) SMN1; SMN2POLBHPGDTP53ADRB2
SCHEMBL7689662 0.85 MAPT (0.48) SMN1; SMN2KMT2AMEN1ALDH1A1MAPT
SCHEMBL7689663 0.85 MAPT (0.48) SMN1; SMN2KMT2AMEN1ALDH1A1MAPT
SCHEMBL7803822 0.84 MEN1 (0.38) SMN1; SMN2HPGDKMT2AMEN1ALDH1A1
SCHEMBL7803819 0.84 MEN1 (0.38) SMN1; SMN2HPGDKMT2AMEN1ALDH1A1
SCHEMBL7692264 0.81 RECQL (0.46) SMN1; SMN2ADRB2KMT2AMEN1MAPT
SCHEMBL7806146 0.81 MEN1 (0.36) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL7795816 0.81 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AMEN1ALDH1A1MAPT
SCHEMBL7806145 0.81 MEN1 (0.36) KMT2AMEN1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337306-B1 HERBICIDES FOR AGRICULTURE RHONE-POULENC AGRO (FR) 2002-01-08 US disclosed
EP-0961766-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES Rhone Poulenc Agro (FR) 1999-12-08 EP disclosed
WO-1998034898-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRO (FR) 1998-08-13 WO disclosed