SCHEMBL7687263

SCHEMBL7687263

CC=C(Oc1ccc(Cl)cc1COC(C)=O)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 2/20 0.40
POLB P06746 2/20 0.40
TP53 P04637 1/20 0.40
ADRB2 P07550 1/20 0.39
GAA P10253 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 2/20 0.38
USP2 O75604 1/20 0.38
MAPT P10636 4/20 0.37
LMNA P02545 1/20 0.36
AMY1A P0DUB6 1/20 0.35
MAPK1 P28482 1/20 0.35
THRB P10828 1/20 0.35
S1PR4 O95977 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7687261 0.90 SMN1; SMN2 (0.42) SMN1; SMN2HPGDPOLBTP53ADRB2
SCHEMBL7687260 0.90 SMN1; SMN2 (0.42) SMN1; SMN2HPGDPOLBTP53ADRB2
SCHEMBL7689664 0.84 MAPT (0.50) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL7803823 0.83 KMT2A (0.40) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL27513782 0.80 SMN1; SMN2 (0.39) SMN1; SMN2HPGDPOLBTP53ADRB2
SCHEMBL13034132 0.80 ADRB2 (0.57) SMN1; SMN2HPGDPOLBTP53ADRB2
SCHEMBL7694772 0.77 TSHR (0.47) SMN1; SMN2HPGDTP53MEN1KMT2A
SCHEMBL7795862 0.75 GAA (0.49) SMN1; SMN2HPGDPOLBTP53GAA
SCHEMBL7795857 0.75 GAA (0.49) SMN1; SMN2HPGDPOLBTP53GAA
SCHEMBL7689662 0.74 MAPT (0.48) SMN1; SMN2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337306-B1 HERBICIDES FOR AGRICULTURE RHONE-POULENC AGRO (FR) 2002-01-08 US disclosed
EP-0961766-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES Rhone Poulenc Agro (FR) 1999-12-08 EP disclosed
WO-1998034898-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRO (FR) 1998-08-13 WO disclosed