SCHEMBL7687552

SCHEMBL7687552

CCCCCNS(=O)(=O)CCCC

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RELA Q04206 4/20 0.62
PPARA Q07869 4/20 0.56
CA2 P00918 5/20 0.52
CA1 P00915 4/20 0.52
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA14 Q9ULX7 2/20 0.52
EPHX1 P07099 1/20 0.50
CA9 Q16790 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10924903 0.98 RELA (0.66) RELAPPARACA2CA1CA12
SCHEMBL10596044 0.98 RELA (0.66) RELAPPARACA2CA1CA12
SCHEMBL7688965 0.98 RELA (0.66) RELAPPARACA2CA1CA12
SCHEMBL4556568 0.95 RELA (0.68) RELAPPARACA2CA1CA12
SCHEMBL7694320 0.93 RELA (0.71) RELAPPARACA2CA1CA12
SCHEMBL10438563 0.93 RELA (0.71) RELAPPARACA2CA1CA12
SCHEMBL18572502 0.93 RELA (0.71) RELAPPARACA2CA1CA12
SCHEMBL7685651 0.93 RELA (0.71) RELAPPARACA2CA1CA12
SCHEMBL7688960 0.93 RELA (0.71) RELAPPARACA2CA1CA12
SCHEMBL8468160 0.93 RELA (0.71) RELAPPARACA2CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002000622-A2 AMINOALCOHOL DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-03 WO disclosed