SCHEMBL7687590

SCHEMBL7687590

C=CCS(=O)(=O)n1ccnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160904 0.73 POLB (0.38)
SCHEMBL27887719 0.73 MEN1 (0.31)
SCHEMBL4947198 0.66
SCHEMBL5259363 0.66
SCHEMBL9543479 0.66
SCHEMBL121557 0.66
SCHEMBL1545809 0.65
SCHEMBL2089384 0.65 HTT (0.44)
SCHEMBL8587432 0.64 TP53 (0.30)
Hydrochloric Acid SCHEMBL27680361 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739349-A CHEMICAL INTERMEDIATE FOR HERBICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-14 US claimed
EP-0661277-B1 Process for making triazolines and new untermediates used therein BAYER AG (DE) 1998-03-11 EP claimed
US-5475115-A Reacting sulfonyltriazole with alkali hydroxide followed by acidification BAYER AKTIENGESELLSCHAFT (DE) 1995-12-12 US claimed
JP-7188186-A None JP disclosed
CN-100334092-C Process for producing cyclic thioether and synthetic intermediate thereof SANKYO CO (JP) 2007-08-29 CN disclosed
CN-1675221-A Process for producing cyclic thioether and synthetic intermediate thereof SANKYO CO (JP) 2005-09-28 CN disclosed
US-6472535-B1 PREPARING A TRIAZOLINONE BY REACTING A TRIAZOLINETHIONE WITH AN OXIDANT IN THE PRESENCE OF A BASE; DOES NOT REQUIRE LONG REFLUX TIMES BAYER CORPORATION 2002-10-29 US disclosed
US-5739349-A CHEMICAL INTERMEDIATE FOR HERBICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
US-5639891-A HERBICIDES; INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-06-17 US disclosed
US-5475115-A Reacting sulfonyltriazole with alkali hydroxide followed by acidification BAYER AKTIENGESELLSCHAFT (DE) 1995-12-12 US disclosed
JP-H07188186-A METHOD FOR PRODUCING TRIAZOLINONE AND NOVEL INTERMEDIATE BAYER AG 1995-07-25 JP disclosed
US-4233059-A HERBICIDES, INSECTICIDES, MITICIDES, FUNGICIDES, NEMATOCIDES SCHERING AKTIENGESELLSCHAFT (DE) 1980-11-11 US disclosed