Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325295 | 0.74 | POLB (0.33) | POLBPKMGAA | |
| SCHEMBL17108819 | 0.74 | POLB (0.41) | POLBPKMGAA | |
| SCHEMBL7687590 | 0.73 | — | — | |
| SCHEMBL8072005 | 0.71 | PKM (0.39) | POLBPKMGAAKDM4EALDH1A1 | |
| SCHEMBL1535216 | 0.69 | POLB (0.47) | POLBPKMGAA | |
| SCHEMBL28225029 | 0.69 | POLB (0.38) | POLBPKMGAA | |
| SCHEMBL1545809 | 0.69 | — | — | |
| SCHEMBL27970026 | 0.69 | GAA (0.34) | POLBPKMGAA | |
| SCHEMBL8587432 | 0.69 | TP53 (0.30) | — | |
| SCHEMBL17108826 | 0.67 | POLB (0.36) | POLBPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003064079-A | HETEROCYCLIC ALKYLSULFONYLPYRAZOLE ANTIINFLAMMATORY/ ANALGESIC AGENT | PFIZER PROD INC | 2003-03-05 | — | — | JP | disclosed |
| EP-0772579-B1 | BENZOYL DERIVATIVES AND SYNTHESIS THEREOF | MONSANTO CO (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0772579-A1 | BENZOYL DERIVATIVES AND SYNTHESIS THEREOF | MONSANTO COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002485-A1 | BENZOYL DERIVATIVES AND SYNTHESIS THEREOF | MONSANTO COMPANY (US) | 1996-02-01 | — | — | WO | disclosed |