Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946910 | 0.97 | CES2 (0.55) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL8509415 | 0.96 | CES2 (0.58) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL17947466 | 0.96 | CES2 (0.58) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL17946904 | 0.95 | CES2 (0.52) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL13182495 | 0.95 | CES2 (0.52) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL17951967 | 0.95 | CES2 (0.52) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL17946938 | 0.95 | CES2 (0.55) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL17947432 | 0.93 | CES2 (0.49) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL9660288 | 0.93 | CES2 (0.44) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL20129293 | 0.93 | CES2 (0.44) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017684-B1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AG (DE) | 2002-11-20 | — | — | EP | disclosed |