Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77722 | 0.81 | F10 (0.44) | F10 | |
| SCHEMBL3103779 | 0.77 | F10 (0.46) | F10MLYCDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL76876 | 0.73 | F10 (0.46) | F10MLYCDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL76877 | 0.73 | F10 (0.45) | F10MLYCDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4214502 | 0.72 | F10 (0.43) | F10MLYCDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL76355 | 0.72 | F10 (0.47) | F10 | |
| SCHEMBL76576 | 0.70 | F10 (0.47) | F10 | |
| SCHEMBL76757 | 0.69 | MAPT (0.40) | F10CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL85545 | 0.68 | F10 (0.64) | F10 | |
| SCHEMBL7734355 | 0.66 | F10 (0.45) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129373-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |