Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6614572 | 0.81 | MEN1 (0.68) | MEN1KMT2APOLB | |
| SCHEMBL6617044 | 0.81 | MEN1 (0.68) | MEN1KMT2APOLB | |
| SCHEMBL6618481 | 0.81 | MEN1 (0.55) | MEN1KMT2A | |
| SCHEMBL7687860 | 0.81 | MEN1 (0.55) | MEN1KMT2A | |
| SCHEMBL6633812 | 0.78 | MEN1 (0.62) | MEN1KMT2APOLB | |
| SCHEMBL7679292 | 0.78 | MEN1 (0.62) | MEN1KMT2APOLB | |
| SCHEMBL6614678 | 0.75 | MEN1 (0.58) | MEN1KMT2A | |
| SCHEMBL6618053 | 0.74 | MEN1 (0.68) | MEN1KMT2APOLB | |
| SCHEMBL6633687 | 0.74 | MEN1 (0.68) | MEN1KMT2APOLB | |
| SCHEMBL6616133 | 0.74 | MEN1 (0.68) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |