Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 17/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.39 |
| ▸ | HTR3B | O95264 | 5/20 | 0.39 |
| ▸ | HTR3A | P46098 | 5/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060558 | 0.84 | CHRNA7 (0.67) | CHRNA7CHRNB2CHRNA4HDAC6HTR3E | |
| SCHEMBL7540721 | 0.83 | CHRNA7 (0.42) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6804367 | 0.82 | CHRNA7 (0.65) | CHRNA7CHRNB2CHRNA4HDAC6HTR3E | |
| SCHEMBL7057901 | 0.82 | CHRNA7 (0.65) | CHRNA7CHRNB2CHRNA4HDAC6HTR3E | |
| SCHEMBL7061685 | 0.81 | CHRNA7 (0.52) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL7064139 | 0.81 | CHRNA7 (0.49) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL7593599 | 0.80 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7063912 | 0.80 | CHRNA7 (0.64) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL7062672 | 0.80 | CHRNA7 (0.48) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B | |
| SCHEMBL7062719 | 0.80 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500840-B2 | CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY | 2002-12-31 | — | — | US | disclosed |