Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP12 | P39900 | 3/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684412 | 0.85 | MEN1 (0.51) | POLBNPC1RAB9ASRD5A2IDO1 | |
| SCHEMBL699482 | 0.84 | FLT3 (0.60) | POLBNPC1RAB9AFLT3IDO1 | |
| SCHEMBL700753 | 0.83 | SRD5A2 (0.73) | POLBNPC1RAB9ASRD5A2MEN1 | |
| SCHEMBL6704768 | 0.83 | KMT2A (0.49) | POLBNPC1RAB9ASRD5A2IDO1 | |
| SCHEMBL6595625 | 0.82 | SRD5A2 (0.77) | POLBNPC1RAB9ASRD5A2FLT3 | |
| SCHEMBL217459 | 0.81 | FLT3 (0.66) | POLBNPC1RAB9AFLT3IDO1 | |
| SCHEMBL913914 | 0.80 | FLT3 (0.68) | POLBNPC1RAB9ASRD5A2FLT3 | |
| SCHEMBL29414307 | 0.80 | FLT3 (0.68) | POLBNPC1RAB9ASRD5A2FLT3 | |
| SCHEMBL16632523 | 0.79 | SRD5A2 (0.67) | POLBNPC1RAB9ASRD5A2FLT3 | |
| SCHEMBL30741601 | 0.77 | IDO1 (0.61) | NPC1RAB9ASRD5A2FLT3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |