Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP12 | P39900 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688230 | 0.85 | POLB (0.63) | MEN1KMT2APOLBSRD5A2RAB9A | |
| SCHEMBL6597064 | 0.85 | SRD5A2 (0.52) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL700701 | 0.84 | HPGD (0.56) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL6704768 | 0.83 | KMT2A (0.49) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL5564109 | 0.81 | KMT2A (0.57) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL6240318 | 0.79 | KDM4E (0.60) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL30403281 | 0.79 | KDM4E (0.60) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL28265787 | 0.78 | KMT2A (0.52) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL22939217 | 0.78 | ALDH1A1 (0.63) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL6804626 | 0.75 | SRD5A2 (0.55) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |