Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ITGAM | P11215 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 5/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666290 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BITGB2ITGAMMIF | |
| SCHEMBL7674119 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BITGB2ITGAMF2 | |
| SCHEMBL7527828 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BRAB9AITGB2ITGAM | |
| SCHEMBL7534732 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BRAB9AITGB2ITGAM | |
| SCHEMBL7670581 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BITGB2ITGAMMIF | |
| SCHEMBL7670126 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BITGB2ITGAMMIF | |
| SCHEMBL7382296 | 0.81 | MIF (0.38) | ITGB3ITGA2BRAB9AMIFHDAC6 | |
| SCHEMBL7668031 | 0.81 | MIF (0.38) | ITGB3ITGA2BRAB9AMIFHDAC6 | |
| SCHEMBL7661330 | 0.80 | MIF (0.52) | ITGB3ITGA2BRAB9AMIFHDAC6 | |
| SCHEMBL7672114 | 0.80 | ITGB3 (0.42) | ITGB3ITGA2BITGB2ITGAMMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455560-B1 | SUBSTITUTED (1-((3-ISOXAZOLIN-5-YL)CARBONYL/METHYL) -4-PIPERIDINYL) ACETIC ACID FOR USE IN INHIBITING THE BINDING OF FIBRINOGEN TO BLOOD PLATELETS AND FOR INHIBITING THE AGGREGATION OF BLOOD PLATELETS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-24 | — | — | US | disclosed |