Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | SCN2B | O60939 | 1/20 | 0.44 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691474 | 0.88 | SMYD3 (0.48) | SCN9ASCN5ACYP3A4CYP2C9CSNK2A2 | |
| SCHEMBL7688928 | 0.87 | P4HTM (0.48) | SCN9ASCN5ACYP3A4CYP2C9CSNK2A2 | |
| SCHEMBL7693447 | 0.84 | SCN9A (0.47) | SCN9ASCN5ACYP3A4CYP2C9CSNK2A2 | |
| SCHEMBL2173115 | 0.84 | PLK1 (0.52) | SMYD3 | |
| SCHEMBL7691939 | 0.83 | P4HTM (0.52) | P4HTM | |
| SCHEMBL7693534 | 0.83 | SMYD3 (0.47) | SCN9ASCN5ACYP3A4CYP2C9CSNK2A2 | |
| SCHEMBL7691836 | 0.82 | PPARG (0.50) | SCN9ASCN5ACYP3A4CYP2C9SMYD3 | |
| SCHEMBL24725139 | 0.82 | SMYD3 (0.46) | SMYD3 | |
| SCHEMBL22972033 | 0.81 | SMYD3 (0.48) | CYP3A4SMYD3 | |
| SCHEMBL22971925 | 0.81 | SMYD3 (0.48) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |