Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688331 | 0.87 | SCN9A (0.53) | P4HTMSCN9ASCN5ACYP2C9CYP3A4 | |
| SCHEMBL7691474 | 0.84 | SMYD3 (0.48) | SCN9ASCN5ACYP2C9CYP3A4SMYD3 | |
| SCHEMBL19880107 | 0.82 | RET (0.49) | SMYD3NPC1RAB9AOGAALDH1A1 | |
| SCHEMBL7693447 | 0.80 | SCN9A (0.47) | SCN9ASCN5ACYP2C9CYP3A4SMYD3 | |
| SCHEMBL2173115 | 0.80 | PLK1 (0.52) | SMYD3NPC1RAB9A | |
| SCHEMBL7691939 | 0.79 | P4HTM (0.52) | P4HTM | |
| SCHEMBL7693534 | 0.79 | SMYD3 (0.47) | SCN9ASCN5ACYP2C9CYP3A4SMYD3 | |
| SCHEMBL7691836 | 0.78 | PPARG (0.50) | SCN9ASCN5ACYP2C9CYP3A4SMYD3 | |
| SCHEMBL24725139 | 0.78 | SMYD3 (0.46) | SMYD3NPC1RAB9AOGA | |
| SCHEMBL22972033 | 0.77 | SMYD3 (0.48) | CYP3A4SMYD3NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |