⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26962783 | 0.97 | — | — | |
| SCHEMBL767020 | 0.79 | — | — | |
| SCHEMBL16307599 | 0.79 | — | — | |
| SCHEMBL31313018 | 0.79 | — | — | |
| Amifampridine SCHEMBL21273 | 0.75 | — | — | |
| Amifampridine SCHEMBL29354458 | 0.75 | — | — | |
| SCHEMBL29518741 | 0.75 | — | — | |
| SCHEMBL3717170 | 0.75 | — | — | |
| Amifampridine SCHEMBL19410631 | 0.72 | GAA (0.56) | — | |
| Amifampridine SCHEMBL30609183 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051301-A1 | MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2025-02-13 | — | — | US | disclosed |
| CN-118786119-A | Mutant IDH1 and IDH2 inhibitors and application thereof | 贝达药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-117551262-A | Liquid crystal copolyester and preparation method thereof | 海利得新材料研究(上海)有限公司 | 2024-02-13 | — | — | CN | disclosed |
| US-20230380280-A1 | ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES | Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230380280-A1 | ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES | Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) | 2023-11-23 | — | — | US | disclosed |
| WO-2023174235-A1 | MUTANT IDH1 AND IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2023-09-21 | — | — | WO | disclosed |
| CN-114391012-A | Pyridine derivatives as KIF18A inhibitors | 美国安进公司 | 2022-04-22 | — | — | CN | disclosed |
| US-9670192-B2 | Substituted isoxazole derivatives | BASF SE (DE) | 2017-06-06 | — | — | US | disclosed |
| EP-2475659-B1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2015-10-28 | — | — | EP | disclosed |
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-10-23 | — | — | US | disclosed |
| US-8435976-B2 | 4-substituted pyridin-3-yl-carboxamide compounds and methods of use | F. HOFFMANN-LA ROCHE (CH) | 2013-05-07 | — | — | US | disclosed |
| EP-2475659-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| US-20120071516-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071516-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| WO-2011029802-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-17 | — | — | WO | disclosed |
| US-20110059961-A1 | 4-SUBSTITUTED PYRIDIN-3-YL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. | 2011-03-10 | — | — | US | disclosed |
| EP-1066289-B1 | PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-1066289-A1 | PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-01-10 | — | — | EP | disclosed |
| US-5959106-A | REACTING A CHLOROSULFONYLARYL COMPOUND WITH AN ARYLAMINE IN PRESENCE OF ORGANIC ALCOHOL SOLVENT | DOW AGROSCIENCES LLC (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1999037650-A1 | PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 1999-07-29 | — | — | WO | disclosed |