Acetyl Tyrosine

Acetyl Tyrosine

SCHEMBL7688897

CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.CC(C)[C@H](N)C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.58
ACE P12821 7/20 0.53
MME P08473 6/20 0.53
CPA1 P15085 1/20 0.53
ACE2 Q9BYF1 1/20 0.53
SLC7A5 Q01650 1/20 0.53
NAALAD2 Q9Y3Q0 1/20 0.51
LMNA P02545 1/20 0.51
ITGB3 P05106 1/20 0.51
ITGA2B P08514 1/20 0.51
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
GRIA1 P42261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyl Tyrosine SCHEMBL28266147 0.90 FOLH1 (0.62) FOLH1ACEMMECPA1ACE2
Afalanine SCHEMBL7691017 0.89 GNPAT (0.56) ACEMMECPA1ACE2ITGB3
Acetyl Tyrosine SCHEMBL1204300 0.89 FOLH1 (0.66) FOLH1ACEMMECPA1ACE2
Acetyl Tyrosine SCHEMBL8977601 0.89 FOLH1 (0.66) FOLH1ACEMMECPA1ACE2
Acetyl Tyrosine SCHEMBL8977600 0.89 FOLH1 (0.66) FOLH1ACEMMECPA1ACE2
Acetyl Tyrosine SCHEMBL313539 0.89 FOLH1 (0.66) FOLH1ACEMMECPA1ACE2
Acetyl Tyrosine SCHEMBL321220 0.89 FOLH1 (0.66) FOLH1ACEMMECPA1ACE2
Valine SCHEMBL7689739 0.88 ALDH1A1 (0.51) FOLH1ACEMMECPA1ACE2
Acetyl Tyrosine SCHEMBL17763856 0.87 SLC7A5 (0.71) FOLH1ACEMMECPA1ACE2
Acetyl Tyrosine SCHEMBL17763855 0.87 SLC7A5 (0.71) FOLH1ACEMMECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002068586-A2 HIV/FIV PROTEASE INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2002-09-06 WO claimed
WO-2002068586-A2 HIV/FIV PROTEASE INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2002-09-06 WO disclosed