Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | PNP | P00491 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | EDNRA | P25101 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HBB | P68871 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535266 | 0.85 | TK1 (0.85) | TK1 | |
| SCHEMBL17478573 | 0.85 | POLA1 (0.58) | TK1USP2PNPTSHREDNRA | |
| SCHEMBL16082172 | 0.84 | PNP (0.72) | TK1USP2PNPTSHREDNRA | |
| SCHEMBL12786366 | 0.83 | PNP (0.70) | TK1USP2PNPTSHREDNRA | |
| SCHEMBL10649363 | 0.83 | PNP (0.64) | TK1USP2PNPTSHREDNRA | |
| SCHEMBL1506775 | 0.83 | TK1 (1.00) | TK1 | |
| SCHEMBL8444939 | 0.81 | MEN1 (0.80) | TK1USP2PNPTSHREDNRA | |
| SCHEMBL8539795 | 0.80 | TK1 (0.69) | TK1 | |
| SCHEMBL8537887 | 0.79 | TK1 (0.68) | TK1TSHR | |
| SCHEMBL8654298 | 0.79 | PNP (0.52) | TK1USP2PNPTSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002502875-A | — | — | 2002-01-29 | — | — | JP | claimed |
| EP-1061922-A1 | USE OF $i(N)-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 2000-12-27 | — | — | EP | claimed |
| WO-1999040916-A1 | USE OF N-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1999-08-19 | — | — | WO | claimed |