Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.61 |
| ▸ | TK1 | P04183 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | EDNRA | P25101 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HBB | P68871 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HPRT1 | P00492 | 8/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428512 | 0.87 | PNP (0.60) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL27709434 | 0.87 | PNP (0.60) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL9960816 | 0.84 | PNP (0.68) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL29286376 | 0.84 | TK1 (0.76) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL10506454 | 0.83 | TK1 (0.63) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL18521979 | 0.83 | PNP (0.66) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL13397350 | 0.82 | TK1 (0.72) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL874736 | 0.82 | PNP (0.64) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL9806969 | 0.81 | TK1 (0.71) | PNPTK1BLMUSP2TSHR | |
| SCHEMBL23892740 | 0.79 | TK1 (0.70) | PNPTK1BLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359061-B1 | COMBINATORIAL LIBRARIES ARE USEFUL FOR SCREENING IN BIOLOGCAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | claimed |
| US-11839661-B2 | Rapid formation of supramolecular hydrogels by short peptide and bioactive small molecules | BRANDEIS UNIVERSITY (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210128745-A1 | RAPID FORMATION OF SUPRAMOLECULAR HYDROGELS BY SHORT PEPTIDE AND BIOACTIVE SMALL MOLECULES | BRANDEIS UNIVERSITY | 2021-05-06 | — | — | US | disclosed |
| WO-2021060939-A1 | NUCLEIC ACID-BASED SOLID-STATE SINGLE ION CONDUCTOR, ELECTROLYTE COMPRISING SAME, AND LITHIUM ION BATTERY COMPRISING SAME | 울산과학기술원 | 2021-04-01 | — | — | WO | disclosed |
| CN-110337308-A | exon skipping oligomer conjugates for muscular dystrophy | 萨勒普塔医疗公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-110290812-A | exon skipping oligomer conjugates for muscular dystrophy | 萨勒普塔医疗公司 | 2019-09-27 | — | — | CN | disclosed |
| WO-2019035928-A1 | RAPID FORMATION OF SUPRAMOLECULAR HYDROGELS BY SHORT PEPTIDE AND BIOACTIVE SMALL MOLECULES | BRANDEIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |
| CN-109311919-A | Exon skipping oligomers for muscular dystrophy | 萨勒普塔医疗公司 | 2019-02-05 | — | — | CN | disclosed |
| US-6359061-B1 | COMBINATORIAL LIBRARIES ARE USEFUL FOR SCREENING IN BIOLOGCAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |