SCHEMBL7689664

SCHEMBL7689664

CC=C(Oc1ccc(Cl)cc1CO)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 1/20 0.39
ALDH1A1 P00352 6/20 0.38
THRB P10828 1/20 0.38
PTGDR Q13258 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
NPC1 O15118 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7689663 0.89 MAPT (0.48) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7689662 0.89 MAPT (0.48) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7803823 0.88 KMT2A (0.40) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7687263 0.84 SMN1; SMN2 (0.43) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7694772 0.81 TSHR (0.47) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7795857 0.79 GAA (0.49) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7795862 0.79 GAA (0.49) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7803822 0.77 MEN1 (0.38) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL7803819 0.77 MEN1 (0.38) MAPTKMT2AMEN1LMNAALDH1A1
SCHEMBL27513062 0.77 MAPT (0.50) MAPTKMT2AMEN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337306-B1 HERBICIDES FOR AGRICULTURE RHONE-POULENC AGRO (FR) 2002-01-08 US disclosed
EP-0961766-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES Rhone Poulenc Agro (FR) 1999-12-08 EP disclosed
WO-1998034898-A1 PHENOXYACETIC ACID DERIVATIVES AND THEIR USE AS HERBICIDES RHONE-POULENC AGRO (FR) 1998-08-13 WO disclosed