Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688870 | 0.96 | KCNA3 (0.54) | KCNA3TP53MAPTRXFP1ABCG2 | |
| SCHEMBL7547760 | 0.91 | KCNA3 (0.54) | KCNA3TP53MAPTRXFP1ABCG2 | |
| SCHEMBL16150328 | 0.89 | TP53 (0.58) | KCNA3TP53MAPTRXFP1ABCG2 | |
| SCHEMBL7688926 | 0.89 | KCNA3 (0.53) | KCNA3TP53MAPTRXFP1ABCG2 | |
| SCHEMBL4158840 | 0.89 | TP53 (0.55) | KCNA3TP53MAPTRXFP1ABCG2 | |
| SCHEMBL7548319 | 0.87 | MAOB (0.48) | KCNA3ABCG2ACE2ABCB1ABCC1 | |
| SCHEMBL4166834 | 0.86 | TP53 (0.51) | KCNA3TP53MAPTRXFP1ABCG2 | |
| SCHEMBL4167435 | 0.84 | ABCG2 (0.70) | TP53MAPTRXFP1ABCG2ALDH1A1 | |
| SCHEMBL4167438 | 0.83 | KDM4E (0.67) | TP53MAPTRXFP1ABCG2ACE2 | |
| SCHEMBL3723524 | 0.82 | TP53 (0.53) | KCNA3TP53MAPTRXFP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | VERENIGING CHRISTELIJK WETENSCHAPPELIJK ANDERWIJS (NL) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, ABCC8 | KCNA3 1195/4885TP53 730/4885MAPT 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.