Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851944 | 0.92 | EGFR (0.49) | EGFRERBB2MAPTMALT1GALR2 | |
| SCHEMBL7851634 | 0.88 | SCN9A (0.43) | EGFRERBB2MAPTSCN9APDGFRB | |
| SCHEMBL7852279 | 0.88 | EGFR (0.48) | EGFRERBB2MAPTMALT1GALR2 | |
| SCHEMBL7851258 | 0.85 | EGFR (0.44) | EGFRERBB2MAPTMALT1GALR2 | |
| SCHEMBL7854805 | 0.85 | EGFR (0.49) | EGFRERBB2MAPTMALT1GALR2 | |
| SCHEMBL7855000 | 0.84 | EGFR (0.43) | EGFRERBB2MAPTMALT1GALR2 | |
| SCHEMBL7855384 | 0.84 | SCN9A (0.43) | EGFRSCN9APDGFRB | |
| SCHEMBL7855387 | 0.83 | EGFR (0.44) | EGFRSCN9APDGFRB | |
| SCHEMBL7855761 | 0.82 | ALDH1A1 (0.46) | EGFRERBB2MAPTMALT1GALR2 | |
| SCHEMBL7855906 | 0.81 | SCN9A (0.43) | EGFRERBB2SCN9APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539214-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1163242-A2 | BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM | Boehringer Ingelheim Pharma KG (DE) | 2001-12-19 | — | — | EP | claimed |
| WO-2000055162-A2 | BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-21 | — | — | WO | claimed |