Phthalic Acid

Phthalic Acid

SCHEMBL7689919

C=CCc1ccccc1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
ALOX15 P16050 1/20 0.56
KMT2A Q03164 2/20 0.50
APEX1 P27695 1/20 0.46
AKR1C3 P42330 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
TSHR P16473 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 2/20 0.44
CYP2C9 P11712 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allylbenzene SCHEMBL27892656 0.88 PTGER1 (0.47) ALDH1A1ALOX15KMT2AAKR1C3TSHR
Salicylic Acid SCHEMBL3435070 0.88 ALDH1A1 (0.60) ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR
Allylbenzene SCHEMBL28079000 0.88 ALDH1A1 (0.42) ALDH1A1ALOX15KMT2AAPEX1SMN1; SMN2
Allylbenzene SCHEMBL2300303 0.87 MAOB (0.50) ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR
Allylbenzene SCHEMBL27716234 0.87 ALDH1A1 (0.51) ALDH1A1ALOX15KMT2ATSHRCYP3A4
SCHEMBL10429624 0.86 AKR1C3 (0.59) ALDH1A1ALOX15APEX1AKR1C3TSHR
Allylbenzene SCHEMBL27481287 0.85 MAOB (0.48) ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR
Allylbenzene SCHEMBL318129 0.85 MAOB (0.57) ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR
Allylbenzene SCHEMBL27636637 0.85 MAOB (0.57) ALDH1A1ALOX15KMT2ASMN1; SMN2TSHR
Phthalic Acid SCHEMBL11405222 0.85 IDO1 (0.46) ALDH1A1ALOX15KMT2ACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033222-B1 Phase change compositions and methods for selective deposition modeling 3D SYSTEMS INC (US) 2002-12-11 EP claimed
US-6406531-B1 FOR BUILDING THREE-DIMENSIONAL OBJECTS; WAXES HAVING DIFFERENT MELTING POINTS; PHASE CHANGE COMPOSITIONS 3D SYSTEMS, INC. 2002-06-18 US claimed
US-6132665-A FORMING A THREE DIMENSIONAL MULTILAYER OBJECT FOR CONSTRUCTION MATERIALS 3D SYSTEMS, INC. (US) 2000-10-17 US claimed
EP-1033222-A1 Phase change compositions and methods for selective deposition modeling 3D SYSTEMS, INC. (US) 2000-09-06 EP claimed
EP-1033222-B1 Phase change compositions and methods for selective deposition modeling 3D SYSTEMS INC (US) 2002-12-11 EP disclosed
US-6406531-B1 FOR BUILDING THREE-DIMENSIONAL OBJECTS; WAXES HAVING DIFFERENT MELTING POINTS; PHASE CHANGE COMPOSITIONS 3D SYSTEMS, INC. 2002-06-18 US disclosed
US-6132665-A FORMING A THREE DIMENSIONAL MULTILAYER OBJECT FOR CONSTRUCTION MATERIALS 3D SYSTEMS, INC. (US) 2000-10-17 US disclosed
EP-1033222-A1 Phase change compositions and methods for selective deposition modeling 3D SYSTEMS, INC. (US) 2000-09-06 EP disclosed