Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814891 | 0.89 | KDM4E (0.55) | KDM4ETRPV1PTGS1MAPTMEN1 | |
| SCHEMBL6819588 | 0.89 | PTGS1 (0.41) | TRPV1PTGS1MAPTMEN1KMT2A | |
| SCHEMBL7785240 | 0.76 | MAPT (0.52) | KDM4ETRPV1PTGS1MAPTMEN1 | |
| SCHEMBL30279461 | 0.75 | PTGS1 (0.52) | KDM4EPTGS1MAPTMEN1KMT2A | |
| SCHEMBL21391974 | 0.75 | PTGS1 (0.52) | KDM4EPTGS1MAPTMEN1KMT2A | |
| SCHEMBL7785239 | 0.74 | CYP1A2 (0.50) | KDM4ETRPV1PTGS1MAPTMEN1 | |
| SCHEMBL3528827 | 0.72 | MAPT (0.62) | KDM4EPTGS1MAPTMEN1KMT2A | |
| SCHEMBL6819278 | 0.72 | GRM4 (0.62) | KDM4ETRPV1MAPTMEN1KMT2A | |
| SCHEMBL30007749 | 0.72 | TRPV1 (0.58) | KDM4ETRPV1MAPTMEN1KMT2A | |
| SCHEMBL17664532 | 0.72 | KMT2A (0.57) | KDM4ETRPV1PTGS1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410571-B1 | VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-25 | — | — | US | disclosed |