SCHEMBL30007749

SCHEMBL30007749

O=C(Nc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1C(F)(F)F)c1ccccc1F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.58
KDM4E B2RXH2 3/20 0.53
HPGD P15428 1/20 0.50
GAA P10253 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
TLR8 Q9NR97 1/20 0.46
KCNMA1 Q12791 1/20 0.46
AKR1C3 P42330 1/20 0.46
NTRK1 P04629 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
RAB9A P51151 1/20 0.45
GRM4 Q14833 1/20 0.45
TP53 P04637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31425031 0.86 TRPV1 (0.56) TRPV1KDM4EHPGDGAAMEN1
SCHEMBL29396019 0.84 RAB9A (0.56) KDM4EMEN1KMT2AMAPTALDH1A1
SCHEMBL22664755 0.83 KDM4E (0.46) TRPV1KDM4EMAPTALDH1A1SMN1; SMN2
SCHEMBL29733220 0.83 KDM4E (0.46) TRPV1KDM4EMAPTALDH1A1SMN1; SMN2
SCHEMBL6814891 0.82 KDM4E (0.55) TRPV1KDM4EHPGDGAAMEN1
SCHEMBL17664210 0.81 TRPV1 (0.57) TRPV1KDM4EHPGDGAAMEN1
SCHEMBL23271153 0.80 KCNMA1 (0.53) KDM4EGAAMEN1KMT2AMAPT
SCHEMBL29695923 0.80 KCNMA1 (0.53) KDM4EGAAMEN1KMT2AMAPT
SCHEMBL29409934 0.79 TRPV1 (0.46) TRPV1KDM4EHPGDGAAMEN1
SCHEMBL30266808 0.78 MEN1 (0.73) TRPV1KDM4EMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264010-A Meta-diacyl compound and application thereof 河南蓝创作物科学有限公司 2025-01-07 CN disclosed
CN-118908850-A Meta-diamide compound and application thereof as pesticide 深圳大学 2024-11-08 CN disclosed
CN-115724768-B Bisamide compound and preparation method and application thereof 广西思钺生物科技有限责任公司 2024-10-29 CN disclosed
CN-115724768-A Bisamide compound and preparation method and application thereof 广西思钺生物科技有限责任公司 2023-03-03 CN disclosed
CN-112707835-B Bromination method of m-diamide compound 长沙嘉桥生物科技有限公司 2022-10-21 CN disclosed